Lambda-cyhalothrin

Lambda-cyhalothrin, also known as cyhalothrin, is a quick-acting type II pyrethroid and the most powerful pyrethroid insecticide in the world (Xu et al., 2023).

The major life-threatening manifestations of pyrethroid poisoning include seizures, pulmonary edema, and hemorrhage.

The mechanism of toxicity is attributed to changes in ionic conduction across voltage-gated sodium channels, leading to a prolonged hyperexcitable state.  Other channels whose conduction is affected include calcium, and chloride channels.

In addition, direct oxidative damage to tissues has been suggested (hepatotoxicity, nephrotoxicity, neurotoxicity and reproductive toxicity, among others) and oxidative stress seems to be the . . .

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