Halauxifen-methyl is a post-emergent herbicide belonging to the arylpicolinate chemical class,
a newer generation of synthetic auxins.
It mimics the natural plant hormone auxin, leading to uncontrolled growth and eventual death in susceptible broadleaf weeds.
Following oral exposure, halauxifen methyl is rapidly and almost completely hydrolyzed to a weak acid Halauxifen-acid (pKa: 2.84 ± 0.04 at 19.9°C) in the liver. As a result, pre-systemic exposure of the liver is by the parent compound, while systemic exposure is by the acid metabolite. Indeed, Short-term oral toxicity studies with rats on halauxifen-methyl and . . .
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