Chlorantraniliprole insecticide: A cup of coffee may be lethal

Chlorantraniliprole is an Anthranilic Diamide insecticide used to control a range of pests belonging to the order Lepidoptera (butterflies and moths) and some other Coleoptera (beetles), Diptera (flies) and Isoptera (termites) species. Other anthranilamide pesticides include cyantraniliprole and flubendiamide.

Chlorantraniliprole is marketed singly, as Coragen or in combination with other insecticides such as pyrethroid (as Ampligo) or Abamectin (as Voliam Targo)

Anthranilic diamides potently activate ryanodine receptor, resulting in an uncontrolled release of calcium from internal stores in the sarcoplasmic reticulum of muscle cells causing impaired regulation, paralysis and ultimately death of sensitive species.

Ryanodine receptors (RyRs) are responsible for . . .

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