Bentazone is almost completely absorbed after oral administration, poorly metabolised and rapidly excreted mainly via urine (Turcant et al., 2003; EFSA, 2015; Wang et al., 2022). The estimated excretion half-life in rats was 4hrs (U.S. Environmental Protection Agency, 1998).
In mice, more than 95% of the administered radioactivity was recovered in the urine within 48 hours.
Furthermore, bentazon is weakly acidic molecule (pK a 3.3) (Turcant et al., 2003). it has shown moderate acute toxicity in a number of species tested by oral administration, while low toxicity was seen via the dermal and inhalation routes (EFSA, 2015 . . .
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