Acetochlor is a chloroacetanilide herbicide used pre-emergence to control annual grasses and broadleaf weeds in maize, soybean, sorghum, and groundnut cultivation. Its herbicidal activity results from inhibition of protein synthesis in shoot meristems and root tips, impairing cell growth and development.
Acetochlor is rapidly absorbed after oral exposure, with peak plasma concentrations occurring at approximately 12 hours and higher levels observed in females than males. Plasma concentrations subsequently decline biphasically. The compound is eliminated mainly in urine, with limited faecal excretion, and more than half of the administered dose is excreted within 24 hours. Rapid elimination and minimal tissue . . .
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