Toxicology
• Oxyfluorfen inhibits hemoglobin synthesis at concentration that have no adverse effect on cellular proliferation (NLM HSDB database, 2007)
• Diphenyl ether herbicides are protox inhibitors ie inhibit protophorphyrinogen oxidase the second-to-last enzyme in chlorophyll biosynthesis as wellas in the heme synthesis; leads to formation of reactive oxygen species thought to be responsible for oxidative membrane degradation and plant death, in the presence of light. Consequently, there is a theoretical risk of developing variegate porphyria or transient porphyria cutanea tarda-like syndrome after a large acute human exposures (E X T O X N E T, 1996;Fluoride action . . .
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