Toxicology
• Just like triazine, triazinone inhibit aliphatic amino acid synthesis in plants, a non-existent pathway in mammalian species hence a generally low degree of mammalian toxicity of the technical grade (Toxnet, 2006).
• The formulated product might show a different toxicity profile due to the added excipients and vehicle used in the formulation(Toxnet, 2006).
Clinical Manifestation
• Vomiting and diarrhea due to their irritant properties
. • Coma
• Circulatory collapse
• Hepatic necrosis
• Renal failure
• Disseminated intravascular coagulation
• Metabolic acidosis
• Hyperthermia
Clinical Management
• There is no specific antidote
• Management is symptomatic
• Consider gastric lavage after ingestion of a large ingestion of poison if . . .
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