Spina bifida is a birth defect in which the vertebral column is open, often with spinal cord involvement. It occurs when the embryonic neural tube (ie, the embryonic structure that develops into the spinal cord and brain) fail to close during embryonic development. This leaves an aperture large enough to allow part of spinal cord exposed to the vagaries of the external environment leading to physical and chemical damage.
Spina bifida occurs between 17th and 30th day of conception when the mother is not even aware of the pregnancy and when the fetus is the size of a rice grain . . .
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