- Pyrazosulfuron ethyl (PE) is a selective systemic herbicide from the sulfonylurea family, widely used for controlling weeds in various crops including rice
- It has a low acute toxicity in mammals - Acute oral LD₅₀ (mg kg⁻¹) > 5000
- Zhang et al., (2022), found that pyrazosulfuron-ethyl may cause immunotoxicity and behavioral abnormalities (a result of neurotoxicity of pyrazosulfuron-ethyl) in zebrafish embryos (zebrafish is an ideal vertebrate model as their genome are highly homologous to those in humans). Moreover, pyrazosulfuron-ethyl exposure also inhibited motor behavior.
- Pyrazosulfuron-ethyl exposure to zebrafish larvae resulted . . .
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