Exposures to pyrethroids are common but significant toxicity is rare and usually due to allergic reactions.
In rat studies, permethrin LD50 range from 430-4000 mg/ kg; In mice values range from 540-2690 mg/ kg depending on factor including age, sex, solvent and the cis:trans isomer ratios (usually 80:20; 40:60; 25:75), whereby the cis isomers are biologically more active but also more toxic than the trans isomers.
Animal studies showed it is absorbed fast and substantially upon ingestion with a peak concentrations occurring around four hours after ingestion.
Permethrin . . .
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