MAD HONEY DISEASE: INTOXICATING/POISONING EFFECTS, AND TREATMENT

Consumption of honey containing toxins can lead to poisoning/intoxication. There are two types of honey intoxication/poisoning. Consumption of honey containing grayanotoxins (polyhydroxylated cyclic hydrocarbon structures that do not contain nitrogen) termed as mad honey poisoning, and the consumption of honey containing tutin (a neurotoxin from Coraria species of shrubs) is termed tutin honey poisoning (Zhang et al., 2017)
Grayanotoxins occur in necta, pollen grains of plants belonging to family of Ericaceae comprising among others the Rhododendron, Pieris, Agarista and Kalmia genera (Jansen et al., 2012).
the clinico-toxicological properties of grayanotoxin toxicity may vary depending on the toxin . . .

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