Proton pump inhibitors (PPIs) potently inhibit gastric acid secretion, especially during daytime period following a daily single morning dose.
PPIs prevents ulcers and allows any ulcers that exist in the esophagus, stomach, and duodenum to heal.
The currently available PPIs include omeprazole, lansoprazole, pantoprazole, rabeprazole, esomeprazole and dexlansoprazol.
All currently available PPIs are generally well tolerated. However, adverse effects have been reported, the majority of which occur after long-term administration.
Therefore, injudicious use of PPIs including long-term PPI treatment of low grade reflux esophagitis and non-erosive GERD should be avoided, if possible.
It is important to administer . . .
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