Nicosulfuron is a sulfonylurea herbicide that inhibits acetolactate synthase (ALS), an enzyme essential for branched‑chain amino acid synthesis in plants. Since ALS is also found in certain microorganisms, the compound may exert antimicrobial effects in addition to its herbicidal action.
Nicosulfuron is of low acute toxicity by the oral, dermal, inhalational, and intraperitoneal routes (Rat, oral LD50>5000mg/kg bw). It is non-irritant to skin, slightly irritant to the eye, and potentially a skin sensitizer (EFSA Scientific Report 2007; Leposhkin et al.,2013).
Nicosulfuron is absorbed rapidly but partially (about 40% is absorbed) in the rat following . . .
Please Subscribe to continue reading
