Indaziflam is a cellulose biosynthesis inhibitor used as a pre-emergence herbicide to control annual grasses and broad-leaved weeds, and it belongs to the alkylazine group of compounds.
Oral administration of low doses (5–15 mg/kg bw) leads to rapid and almost complete absorption. Indaziflam is widely distributed into systemic circulation (Tmax = 40–60 min). However, single high-dose oral studies (> 550mg/kg/bw) in rats indicate that a large portion (40%) of the parent chemical is excreted unabsorbed or unchanged after absorption, indicating a saturation of the uptake system (Australian Pesticides and Veterinary Medicines Authority [APVMA . . .
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